Sunday, August 30, 2015

x -74 Louis Sheehan

x - 74   Connecticut public officials to prison.

The criminal probe normally would be handled by the U.S. attorney in Eastern Virginia, where the CIA headquarters are located. Instead, Eastern Virginia prosecutors have been recused from the probe. It was Eastern Virginia prosecutors who first alerted a federal judge about the existence of the tapes and their destruction in October. Mr. Mukasey said in a statement that their recusal was made "in order to avoid any possible appearance of a conflict with other matters handled by that office."

CIA Inspector General John L. Helgerson, who worked with the Justice Department on the preliminary inquiry, also recused himself from the investigation.

Government officials have played down the importance the tapes may hold in several continuing or past terror cases. The tapes also weren't shared with the commission that investigated the 9/11 attacks. Critics of the Bush administration have alleged that the destruction of the tapes may amount to destruction of evidence, which is a crime.

CIA spokesman Mark Mansfield said: "The CIA will of course cooperate fully with this investigation as it has with the others into this matter." The CIA has already agreed to open its files to congressional investigators, who have begun reviewing documents at the agency's headquarters.

The House Intelligence Committee has ordered Jose Rodriguez, a former chief of the CIA's National Clandestine Service who directed the tapes be destroyed in late 2005, to appear at a hearing Jan. 16.

Mr.Rodriguez, who was to retire from the agency at the end of last year, has become a focal point in the debate over the tapes' destruction. According to several former colleagues, his goal likely was to protect the officers who conducted the interrogations from criticism and litigation. They have also described him as a cautious operator who probably would have ensured that top CIA managers knew of the plan.

But in trying to avert one scandal, the agency may have spawned a greater controversy. Sen. Chuck Hagel (R., Neb.), a member of the Senate intelligence panel, said last month that it was hard for him to believe "that senior members of the White House somehow didn't pay attention to this or didn't know about it."

The White House said last month that President Bush "has no recollection" of hearing about the tapes or their destruction before he was briefed about the matter in early December.

CIA Director Gen. Michael V. Hayden has said that the tapes were destroyed because the agency feared that the identities of the officers would become public and that they would become targets of al Qaeda.

But former officers familiar with the events have offered a different explanation, saying Mr. Rodriguez had long been concerned that the CIA lacked a long-term plan for handling interrogations. He also worried -- given the response to Abu Ghraib prison in Baghdad -- that lower-level officers would take the fall if the videos became public, they said.

One former official said interrogators' faces were visible on at least one video, as were those of more senior officers who happened to be visiting. He said Mr. Rodriguez was concerned that "they were carrying out the direction from higher-ups in the administration" but that the people who would end up in trouble would be lower-level officials in the bureaucracy. Another former senior intelligence official said, "Jose was concerned about how all this would end. He wasn't getting instructions from anybody."

Mr. Rodriguez's attorney, Robert S. Bennett, had no comment on today's announcement.































































































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It’s probably the happiest root canal ever: Molecular archaeologists reported last January that they had drilled into a 10,300-year-old human tooth discovered in Alaska and extracted genetic gold. The molar, recovered from skeletal remains found in 1996 in On Your Knees Cave, located on Prince of Wales Island off southern Alaska, holds the oldest genetic sample ever recovered in the Americas. That sample supports the theory that humans first arrived here about 15,000 years ago and then migrated down the continent’s western coastline.

Brian Kemp, a molecular anthropologist at Washington State University who led the study, found that out of 3,500 Native Americans examined from a genetic database, 1.5 percent showed the same genetic pattern in their mitochondrial DNA as that found in the ancient tooth. “What’s interesting is that the distribution is almost entirely down the west coast of the Americas, all the way down to Tierra del Fuego,” says Kemp. That, says Theodore Schurr, an anthropologist at the University of Pennsylvania, “lends credence to the reemerging hypothesis that the first modern human populations to arrive in North America and then populate the rest of the Americas used a coastal route to actually get there.”

Kemp also compared the ancient DNA with its related modern DNA to see how fast it mutated over time. This “molecular clock” of mutation rates can be used to calculate when the ancestors of today’s Native Americans first arrived on these shores. Previous estimates pegged their appearance as far back as 40,000 years ago, but Kemp’s newly calibrated clock speeds up the scenario. “Within the last 15,000 years is my bet,” he says.



In the traditional view of photosynthesis, the energy carried by photons streaming from the sun is transferred by bouncing from one chlorophyll molecule to the next, a process that ultimately builds simple carbohydrates from water and carbon dioxide. But last spring, a team led by Graham Fleming, deputy director of the Lawrence Berkeley National Laboratory, reported that the process is much more interesting than that.

Using ultrafast lasers, they found that the interaction between the sun’s energy and the chlorophyll molecules in a bacterium relies on a piece of quantum mechanical weirdness known as superposition, where a single photon’s energy can temporarily be in many different states at once. This allows photosynthesis to probe all the possible reaction pathways within the various chlorophyll molecules. The most efficient pathway is selected and energy is transferred through the bacterium as the superposition collapses.

“This is similar to quantum computing in some sense,” says Greg Engel, a member of Fleming’s team. “This is how quantum computing realizes its incredible efficiency and its ability to solve very complex problems, because it can evaluate many solutions at once.” http://louis-j-sheehan.com


It may seem like simple compassion to give the terminally ill access to experimental drugs not yet approved by the FDA, but some argue it may also jeopardize the effectiveness of clinical trials and leave patients open to exploitation. In August, the U.S. Court of Appeals for the District of Columbia upheld (pdf) the power of the FDA to control patients’ access to unapproved drugs. The court stated that patients do not have a fundamental right to drugs that have not been proven safe.

The Abigail Alliance for Better Access to Developmental Drugs and the Washington Legal Foundation had filed the suit against the FDA. “What we argue in our lawsuit is that the decision should be a patient’s with their doctor,” says Frank Burroughs of the Abigail Alliance. He founded the organization in 2001 after his 21-year-old daughter Abigail died from head and neck cancer. She had been denied access to the experimental drug Erbitux, which was later approved by the FDA. Burroughs says the groups are planning an appeal to the U.S. Supreme Court.

Many legal experts and ethicists argue that access to unapproved drugs would undermine the scientific process that determines which drugs are effective as well as the FDA’s ability to determine drug safety. Only 8 percent of cancer drugs that enter clinical trials earn FDA approval. The bulk are rejected as ineffective or unsafe. “The very, very sick are open to exploitation,” says Arthur Caplan, chairman of medical ethics at the University of Pennsylvania. He also notes that patients may not join clinical trials if they can get the drugs otherwise, which could impair the development of new drugs.

“I think the court got it right,” says Peter Jacobson of the University of Michigan School of Public Health. Jacobson views the FDA’s efforts to extend the compassionate use policy as the better way to handle the issue. “Then you’re able to distribute some of these drugs under some kind of scientific protocol without compromising clinical trials that are needed for long-term understanding.”







The CDC's vaccine advisory panel voted to make shingles vaccination routine for all Americans 60 and older.

Shingles is a painful disease caused by reactivation of dormant varicella zoster virus, or VZV. Best known as the virus that causes chickenpoxchickenpox, VZV is a herpesherpes virus that can come back with a vengeance when a person's immunity wanes with age, disease, or immunity-suppressing drugs.

Without vaccination, about 20% of people who have had chickenpox eventually will get shingles. A person who lives to be 85 has a 50% chance of getting shingles.

Shingles is a bad enough disease to be a good reason to get vaccinated.

But in about a third of cases, shingles turns into an excruciatingly painful disease called postherpetic neuralgia, or PHN. A smaller percentage will get a painful, blinding disease called ophthalmic zoster.

The new vaccine, Merck's Zostavax, won FDA approval last May.

Now the main U.S. vaccine advisory panel -- the Advisory Committee on Immunization Practices (ACIP) -- officially recommends routine use of the vaccine for everyone 60 and older.

The committee voted not to make shingles vaccination routine for people under 60, citing a lack of clinical data on vaccination in that age group.

Similarly, the panel said there was too little data for it to recommend that doctors offer the vaccine for people about to undergo immunity-suppressing treatments.
Good Vaccine, Terrible Disease

A major clinical trial shows the vaccine is more than 60% effective in reducing shingles symptoms. Perhaps most importantly, it reduces painful PHN by at least two-thirds.

"Reducing PHN is the motivation for most of us working on this clinical trial," Michael N. Oxman, MD, of the University of California, San Diego, said in a presentation to the ACIP. "For people with severe PHN, their lives are blighted and the lives of their families are blighted."

PHN pain can last for years. Sudden, lancing pain can quite literally bring patients to their knees. Each year, there are more suicides due to PHN pain than due to cancercancer pain.

And PHN isn't the only bad complication of shingles. Some 15% of shingles patients get ophthalmic zoster -- shingles that affects one or both eyes.




In a public comment, Herbert Kauffman, MD, former chairman of ophthalmology at Louisiana State University, offered the ACIP a graphic description: "This is not going blind in peace and quiet," Kauffman told the ACIP. "This is an all-consuming pain patients live with every moment of every day for years."

The ACIP recommendation means insurers will be more likely to pay for shingles vaccination in 60-and-over patients.


In one of the first studies to detect cancer using RNA in saliva, researchers were able to differentiate patients with head and neck cancer from healthy subjects based on biomarkers found in their saliva, according to an article in the Dec. 15 issue of the journal Clinical Cancer Research.

Researchers at the University of California Los Angeles’ Jonsson Comprehensive Cancer Center reported in the March 2004 issue of Journal of Dental Research that people have about 3,000 clinically distinct types of RNA in their saliva. This discovery led to a novel clinical approach called salivary transcriptome diagnostics.

In a study to evaluate this diagnostic approach’s value, researchers collected unstimulated saliva from 32 subjects with cancers of the mouth, tongue, larynx and pharynx and 32 matched control subjects. When they extracted RNA from the saliva samples, they discovered that 1,679 genes were expressed at significantly different levels in the test subjects’ saliva than in the control subjects’ saliva.

Study results also showed that a combination of four RNA biomarkers provided a detectable signature for head and neck cancer. Researchers conducted a blinded second saliva screening and identified the signature in test subjects with 91 percent sensitivity and specificity.

Louis J Sheehan
Louis J Sheehan, Esquire



Louis J Sheehan Esquire




"We will follow up with a larger cohort of about 200 patients in the near future," said senior author David Wong, D.M.D., D.M.Sc. "This study will hopefully allow us to distinguish in saliva between the various stages of the cancer and ultimately push our accuracy up to as close to 100 percent as possible."



















































































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This is intended as a hopefully helpful, but somewhat lighthearted look at ancient philosophical beliefs that would make five fine New Year's resolutions for today. They are meant as a counter to typical New Year's resolutions, like these:

       1. Lose Weight
       2. Pay Off Debt
       3. Save Money
       4. Get a Better Job
       5. Get Fit
       6. Eat Right
       7. Get a Better Education
       8. Drink Less Alcohol
       9. Quit Smoking Now
      10. Reduce Stress Overall
      11. Reduce Stress at Work
      12. Take a Trip
      13. Volunteer to Help Others
                Source: U.S. Government site

Have you written a list of New year's Resolutions? Does it include something geared to making you more like a Hollywood ideal? Something like losing weight? We start each new year with a clean slate, but as soon as we break down and eat that tempting cream-filled puff pastry, we think we've failed and give up. Might as well have a couple of beers and a a pizza. Oops! By February the scale has moved in the wrong direction. One question we should ask before coming up with the duly anguished-over creative list of new resolutions is whether or not they're the result of social pressure. It may seem easier fitting into someone else's list of shoulds than changing our own attitudes, but if you've ever tried to quit smoking because your family begs you to, you probably know that's not enough.

People compile New Year's Resolutions in an effort to improve specific aspects of themselves, thinking behavior elicited by the resolutions will make them better people. If they volunteer one day a month (making them better in the brotherly-love department) and exercise three times a week (back to conforming to social pressure mode), including a yoga class (eliminating stress one minute at a time), and if they put 10% into a money market account (for retirement, as the news media drums into our heads each December), life will magically improve. Even if it did work, this seems like a piecemeal approach in need of a master plan. And therein lies the beauty of ancient philosophy.

Masterplan: Emulate the Stoics
This list of 5 resolutions includes passages from the writing of leading Roman Stoics, Epictetus (really a Greek, but he lived in Rome), Marcus Aurelius, and Seneca, with applications or parallels in the modern (or at least post-classical) world. The Stoics have had a profound influence on Christianity and modern philosophy, so the ideas may seem very familiar. There are even sayings and modern song lyrics reflecting the Stoic philosophy. One problem of the Stoics for our contemporary, secular world is the ongoing references to god. This god is really more like reason, nature, or logos, but may still cause trouble for non-theists. To avoid this, I have attempted to minimize the god-context in my selections.












The Stoics believed in one basic behavior: being good. People do this by, among other things,

   1. living according to nature,
   2. helping others,
   3. commitment to self-improvement routines,
   4. being dutiful, which may include attempting to persuade others of one's beliefs, and
   5. central to all else, maintaining a proper attitude.

The good person is not evil. He also happens to be a philosopher. This may be another sticking point for moderns, but the self-help books so popular today are like philosophy, so if the idea of being a philosopher is too profound, consider these suggestions as well-testified popular psychology instead of philosophy.

1. Live According to Nature: To Everything There Is a Season
Stoicism comes from the Hellenistic period of ancient Greece, which began around 300 B.C. There was no electricity. There were no in vitro pregnancies. Most people used their own feet for transportation. People followed the natural cycles of day, night, and the seasons. Everything took time. We've been spoiled by artificial light, microwave ovens, airplanes, and other conveniences, so we no longer have to worry much about natural cycles. Instead, we impatient multi-taskers try to cram everything in. This means that however much the ancient Stoics might have had to struggle to try to live according to nature, we've got to work even harder.

    No great thing is created suddenly, any more than a bunch of grapes or a fig. If you tell me that you desire a fig, I answer you that there must be time. Let it first blossom, then bear fruit, then ripen.
    - Epictetus: Discourses Chap. xv.












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Louis J Sheehan








Louis J Sheehan, Esquire

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Louis J Sheehan Esquire



Stoics believed in the idea of one universal human family. Just as it is contrary to nature to cut off your nose to spite your face, so it is contrary to nature to hurt members of your family, even if accepting people without being annoyed by them requires patience.

    For we are made for co-operation, like feet, like hands, like eyelids, like the rows of the upper and lower teeth. To act against one another then is contrary to nature; and it is acting against one another to be vexed and to turn away.
    - Marcus Aurelius: Meditations Book II















2. Help Your Fellow Man: Do Unto Others
We are all members of the human family. In recent years we've heard that it takes a village to raise a child and many of the countries of Europe joined together into the European Union. In these and many other ways, we see that we are all in it together. The Stoics wrote about it, and in 1624, so did John Donne (Meditation XVII):

    No man is an island, entire of itself; every man is a piece of the continent, a part of the main. If a clod be washed away by the sea, Europe is the less, as well as if promontory were, as well as if a manor of thy friend's or of thine own were. Any man's death diminishes me, because I am involved in mankind; and therefore never send to know for whom the bell tolls; it tolls for thee.

Because we are all part of one "family," we should work to its good and not try to separate ourselves.

    As thou thyself, whoever thou art, were made for the perfection and consummation, being a member of it, of a common society; so must every action of thine tend to the perfection and consummation of a life that is truly sociable. What action soever of thine therefore that either immediately or afar off, hath not reference to the common good, that is an exorbitant and disorderly action; yea it is seditious; as one among the people who from such and such a consent and unity, should factiously divide and separate himself.
    - Marcus Aurelius: Meditations XXI

    Labour not as one to whom it is appointed to be wretched, nor as one that either would be pitied, or admired; but let this be thine only care and desire; so always and in all things to prosecute or to forbear, as the law of charity, or mutual society doth require.
    - Marcus Aurelius: Meditations 9.X

Helping others is acting according to nature, but it also has beneficial personal repercussions.

    Wouldst thou have men speak good of thee? speak good of them. And when thou hast learned to speak good of them, try to do good unto them, and thus thou wilt reap in return their speaking good of thee.
    - Epictetus: Golden Sayings L










3. Develop Good Habits: Practice Makes Perfect
Many modern resolutions fall under this heading. You should not set impossible standards, but you should constantly work on getting better:

    Practise yourself, for heaven's sake, in little things; and thence proceed to greater.
    - Epictetus: Discourses Chap xviii.

    Whatever you would make habitual, practise it; and if you would not make a thing habitual, do not practise it, but habituate yourself to something else.
    - Epictetus: How the Semblances of Things Are to Be Combated. Chap. xviii.

What makes the Stoic habit-development different is that the causes championed by repetition make you a better person. The Stoics even envisioned breaking of a bad habit by repetition. No going cold turkey for anger management here:

    Reckon the days in which you have not been angry. I used to be angry every day; now every other day; then every third and fourth day; and if you miss it so long as thirty days, offer a sacrifice of thanksgiving to God.
    - Epictetus: How the Semblances of Things Are to Be Combated. Chap. xviii.

If you don't know which habits you should develop, the Stoics have a list, albeit somewhat generic and obscure. You should develop the habit of avoiding evil, getting experience in your strengths, making wise decisions, and, appropriately enough, forming careful resolutions:

    Shall I show you the muscular training of a philosopher? "What muscles are those?" -- A will undisappointed; evils avoided; powers daily exercised; careful resolutions; unerring decisions.
    - Epictetus: Wherein consists the Essence of Good. Chap. viii.









4. Do Your Duty
Winston Churchill said, "All the great things are simple, and many can be expressed in a single word: freedom; justice; honor; duty; mercy; hope." Being part of the universe means you have duty. The sun has the duty to shine. The earth has the duty to rotate on its axis and make a yearly circuit of the sun. The bee has a duty to make honey. And humans have the duty to act so as to be good.

    As it is the duty of the universe to maintain the round of the seasons, as it is the duty of the sun to vary the points of his rising and setting, and to do all these things by which we profit, without any reward, so is it the duty of man, amongst other things, to bestow benefits. Wherefore then does he give? He gives for fear that he should not give, lest he might lose an opportunity of doing a good action.
    - Seneca: On Benefits 4.12

We also have the duty to keep our promises, all other things remaining equal. We should not, however, fret over reneging should we learn that our promise breaks the law or means going out when we have a fever.

    When I promise to bestow a benefit, I promise it, unless something occurs which makes it my duty not to do so. What if, for example, my country orders me to give to her what I had promised to my friend? .... I shall be treacherous, and hear myself blamed for inconsistency, only if I do not fulfil, my promise when all conditions remain the same as when I made it; otherwise, any change makes me free to reconsider the entire case, and absolves me from my promise.
    - Seneca: On Benefits 4.35

The Stoics have, not too surprisingly, rather a lot to say in the area of encouraging people to do their duty, since duty is, after all, not the fun stuff. Duty varies. Sometimes duty requires helping others with money; at other times, advice.

    Do not grow weary, perform your duty, and act as becomes a good man. Help one man with money, another with credit, another with your favour; this man with good advice, that one with sound maxims.
    - Seneca: On Benefits I.2

    Men must be taught to be willing to give, willing to receive, willing to return; and to place before themselves the high aim, not merely of equalling, but even of surpassing those to whom they are indebted, both in good offices and in good feeling; because the man whose duty it is to repay, can never do so unless he out-does his benefactor;
    - Seneca: On Benefits I.4






5. Adjust Your Attitude: You Get What You Need
You can't always get what you want, but you can change your attitude so you no longer want it. If for instance, you are robbed, you are likely to feel that you are the aggrieved party, but there is, actually another way to look at it. You lost your wallet, but what did the thief lose?

    The reason why I lost my lamp was that the thief was superior to me in vigilance. He paid however this price for the lamp, that in exchange for it he consented to become a thief: in exchange for it, to become faithless.
    - Epictetus: Golden Sayings XII

This is the area where we have the greatest control. If we do as the Stoics encourage, do nothing to hurt the community, act with deliberation, kindness

    Let this be thy only joy, and thy only comfort, from one sociable kind action without intermission to pass unto another,
    - Marcus Aurelius: Meditations 6.6

and care, and show true humility

    Do nothing against thy will, nor contrary to the community, nor without due examination, nor with reluctancy. Affect not to set out thy thoughts with curious neat language. Be neither a great talker, nor a great undertaker.
    - Marcus Aurelius: Meditations III. 5

we just might find we get what we need.

    When we are invited to a banquet, we take what is set before us; and were one to call upon his host to set fish upon the table or sweet things, he would be deemed absurd. Yet in a word, we ask the Gods for what they do not give; and that, although they have given us so many things!
    - Epictetus: Golden Sayings XXXV



































                 
        
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Mukasey Opens Criminal Probe
Into Destruction of CIA Tapes
By EVAN PEREZ
January 2, 2008 5:02 p.m.

The Justice Department opened a criminal investigation into the Central Intelligence Agency's destruction of videos showing detainee interrogations of top al Qaeda suspects and appointed an outside prosecutor to handle the probe.

Attorney General Michael Mukasey said that a joint preliminary inquiry opened Dec. 8 by his department's National Security Division and the CIA's inspector general determined "there is a basis for initiating a criminal investigation of this matter."
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Born: June 23, 1892 - Lemberg (Lvov), Poland
Died: May 22, 1993 - Philadelphia, PA, USA

The Polish-born pianist, Mieczyslaw Horszowski, was taught to play the piano by his mother, a student of one of Chopin's students, and his main teacher, Theodor Leschetizky, was a protégé of Carl Czerny. Horszowski was playing (and transposing) Bach inventions at age five; at eight he was presented to the public as a prodigy, and at ten he began his formal career. He played for Fauré and perhaps Camille Saint-Saëns in 1905 and made his USA debut, at Carnegie Hall, the following year. It was also during 1906 that he met the youthful Pablo Casals and Arturo Toscanini, who became lifelong friends and collaborators. Horszowski was especially noted as a chamber music pianist and became a fixture of Casals' Prades Festival for many years.

Interrupting his high-flying career to pursue a humanities degree at the Sorbonne in Paris from 1911 to 1913, Mieczyslaw Horszowski moved to Milan during the war and remained there until 1939, touring internationally. As World War II broke out he was appearing in Brazil, and instead of returning to Europe he headed for the USA, where he remained for the rest of his life. He quickly found performing opportunities with Toscanini's NBC Symphony Orchestra, and he began teaching at Philadelphia's Curtis Institute in 1942. He was a fixture of New York's recital scene, performing complete cycles of Beethoven's piano works and Mozart sonatas and concertos, and he appeared at the White House in 1961 and 1978. Horszowski was the first person to record while playing the first known piano constructed, an instrument built in 1720 by Bartolomeo Cristofori and housed in the collection of the Metropolitan Museum of Art in New York.

In 1981, at age 89, Mieczyslaw Horszowski married for the first time; his wife was Italian pianist Beatrice Costa. His eyesight declined, which put an end to his concerto and chamber music performances, but he continued his solo recital career, performing from memory. He performed his last recital at age 99, slightly more than a year before his death in 1993. At the Curtis Institute he taught an impressive roster of students, including Anton Kuerti, Murray Perahia, and Richard Goode.

Mieczyslaw Horszowski played a range of music but focused on Bach, Beethoven, and Chopin, and even in his last years he essayed difficult works like Beethoven's Diabelli Variations. Although his recording career only goes back to 1936, the traditions of playing he represented are much older than that, dating back to the early Romantic era.


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